Courses in blue will be offered in the Spring semester, 2015.
BIOL100. Principles of Biology. Introductory biology course for non-majors that covers major principles in biology as they relate to higher organisms. When possible, the human organism is selected to illustrate a principle. Fall and Spring. Three 50-minute periods, one 3-hour laboratory. Felise
BIOL102. Biology of the Birds. Introduction to avian origin and evolution. Topics include theories of flight, migration, behavior, distribution, and concepts relating to territory, courtship, and mating. Laboratories include field trips to identify local bird species and study their behavior and ecology. Cannot be used as a biology elective in the major. Summer and Fall. Saturday field trips. Klem
BIOL103. Human Anatomy and Physiology I. Introduction to concepts and principles important to the understanding of the human body, with clinical applications. Structure and function of tissue, integumentary, skeletal, muscular, articulation, nervous, sensory, and endocrine systems. Fall. Three 50-minute periods, one 3-hour laboratory. Fox
BIOL104. Human Anatomy and Physiology II. Second course in the anatomy and physiology sequence. Emphasis on understanding structure and function of the human systems with emphasis on clinical applications. Topics include digestive, respiratory, vascular, lymphatic, immune, excretory, and reproduction systems; early development; genetics. Prerequisite: Biology 103 or permission of instructor. Three 50-minute periods, one 3-hour laboratory. Fox
BIOL107. Environmental Science. Introduces non-major students to fundamental principles of ecology and the relationship of humans to their environment. Topics include agriculture and food production, water and air pollution, energy use and associated environmental effects, toxic waste, and renewable/nonrenewable resources. resources. Fall. Two 70-minute periods, one 3-hour laboratory. Husic
BIOL112. General Zoology. An introduction to basic concepts in biology through study of the major lineages of invertebrate and vertebrate animals, with emphasis on the ontogeny, structure, and function of organ systems in an evolutionary context. Topics covered will include basic structure and function, development, systematics, and evolution. The laboratory will focus on observation of structural-functional relationships of living and preserved representatives of the major animal phyla. Three 50-minute periods, one 3-hour laboratory. Irish
BIOL119. Introductory Botany. Introduction to plant science, with attention to historical and cultural importance of plants, structure and function of higher plants, survey of major plant divisions. Laboratory emphasizes relationship between structure and physiological function in major plant divisions. One of two introductory courses for the major. Fall and Spring. Three 50-minute periods, one 3-hour laboratory. Bevington
BIOL205. Pathophysiology. Mechanisms of disease in humans. Emphasis is on dysfunction at cellular, tissue, and organ levels. Chemical, physical, and genetic stress factors are examined to understand how they affect human systems. Prerequisite: Biology 103–104. Fall. Two 70-minute periods. Specht
BIOL206. Microbiology for the Health Sciences. Introductory course for students in health science curricula. Presents biomolecules of life, enzyme interaction, physiology, structure of representative microorganisms and principles of microbial control and chemotherapy. Emphasizes bacteria, viruses, fungi, and protozoa of health significance and the host-parasite relationship. Microbiological techniques will be emphasized in laboratory. Cannot be used as a biology elective in the major or minor. Prerequisites: Biology 103–104 and Chemistry 108. Three 50-minute periods, two 90-minute laboratories. Felise
BIOL209. Humans and the Global Ecosystem. Increases in human population and advances in technology allow humans to modify or destroy ecosystems at a rate unimaginable a century ago. We will examine current trends associated with environmental change in order to understand what they mean for us and other species with which we share the biosphere. Environmental issues are viewed through the lenses of economics, politics, and culture. Topics include ecology, population growth, environmental ethics, ecological economics, sustainable development, and the loss of biodiversity and the forces that cause it. Fall. Two 70-minute periods. Bevington
BIOL210. Genetics. Introductory course with emphasis on eukaryotic organisms. Classical and contemporary aspects of genetics. Prerequisite: sophomore standing. Fall. Three 50-minute periods, one 3-hour laboratory. Jones
IDIS213. The Impact of Technology on Diet and Disease. Historically, technology has had an enormous impact on diet and disease. Beginning with the domestication of crops and animals, the course will trace changes in the diet and human social systems resulting from advances in agriculture and food distribution. Topics include the 18th-century agricultural and industrial revolutions and the "green revolution" of the 1950s; hormones, antibiotics, genetically engineered crops; pandemics such as the Black Death of the 14th century, Spanish influenza in 1918, and AIDS and other emerging diseases. This course does not meet the requirements for the biology major or minor. Two 70-minute periods. Binford, Husic
IDIS217. From Ape to Madonna: The Evolution of Humankind. One of the most profound questions that human beings can ask of themselves has to be, "Where do we come from?" This course will deal with the historical and comparative bio-anthropology of our species, looking at humans as members of the animal kingdom, focusing on the attributes shared with our primate relatives, and exploring the origins of uniquely human attributes. Using the approaches of evolutionary biology, physical anthropology, and archaeology, this course traces human physical evolution and cultural development from its earliest beginning, more than five million years ago, to about 15,000 years ago, just before the beginnings of plant and animal domestication and the rise of complex societies. In addition, this course will pay special attention to the impact that evolutionary ideas have had on social, political, and educational issues in American life. This course does not meet the requirements for the biology major or minor. Three 50-minute periods. Kuserk
BIOL230. Field Botany. Introduction to plant systematics and ecology. In systematics, focus is on our concept of species: patterns and sources of variation in plant populations, compatibility and breeding systems, hydridization and introgression, and polyploidy; in ecology, the nature of local plant communities and forces that shape them. Fieldwork includes sampling of plant communities, collecting and identifying specimens, visiting botanical institutions. Prerequisite: Biology 119. Fall. Alternate years. Two 50-minute periods, two 3-hour laboratories. Bevington
BIOL235. Microbiology. Nature and activities of microorganisms as seen through their morphology, physiology, genetics, biochemistry, and ecology. Special attention on the microbe as an infectious agent through investigation of host-microbe interaction, action of antibiotics, and immunological responses of host organisms to infection. Prerequisites: Biology 103–104, 112 or 119 and Chemistry 108 or 113–114. Fall. Three 50-minute periods, two 120-minute laboratories. Felise
BIOL250. Animal Behavior (also Psychology 250). Neurological, ecological, and genetic basis of behavior, with emphasis on evolutionary mechanisms that govern acquisition of behavioral patterns. Prerequisite: Biology 100 or 112, or Psychology 120. Alternate years. Three 50-minute periods, one 3-hour laboratory. Kuserk
BIOL262. Human Genetics. An applied genetics course which reviews Mendelian patterns of inheritance, chromosomal syndromes, molecular genetic implications in oncogenetics and immunogenetics, strategies of gene therapy, genetic counseling methods, and related population genetic concepts. Prerequisite: Biology 210 or permission of instructor. Three 50-minute periods, one 3-hour laboratory. Staff
BIOL265. Cell Physiology. Introduction to biochemical and physiological activities of cells. Topics include metabolic pathways, bioenergetics, enzyme kinetics, membrane structure and function, molecular biology of the gene, cell motility, and cellular differentiation. Prerequisites: Biology 112 or 119 and Chemistry 113–114. Three 50-minute periods, one 3-hour laboratory. Bevington
BIOL291.2. Special Topic: Quantitative Methods in the Life and Environmental Sciences. The course covers the fundamental concepts and methods of statistical analyses as they are employed in the life and environmental sciences. This includes a review of probability theory and distributions, particularly those distributions most commonly encountered in the disciplines. The course will emphasize the methods students are most likely to encounter, with special emphasis on the practical aspects of sampling and experimental design. Topics covered include descriptive statistics, graphical displays of data, probability, confidence intervals and tests for means, differences of means, proportions, differences of proportions, chi-square tests for categorical variables, regression and correlation, and analysis of variance. Fall. One 70-minute period. Kuserk
BIOL292. Special Topic: Aquatic Biology. An introduction to the ecology of inland waters, including lakes, ponds, wetlands and streams. Major topics include geologic origins, typology, geographic distribution, biota, ecological succession, ecosystem function and restoration/management as applied to freshwater habitats, Emphasis is placed on the interaction between organisms and the environment. Laboratories include use of field equipment, field research techniques, and identification of aquatic organisms, including protozoa, invertebrates, fish, herpetofauna and plants. Many laboratories will be conducted out of doors, and there is one required field trip off campus. Two 70-minute periods, one 3-hour laboratory. Kuserk
BIOL293. Special Topic: Immunology and Pathology. Although most human-microbe interactions are harmless or even helpful, a few result in disease. In this course we will explore the complex interplay that exists between a pathogen and its host and how it results in disease. Microorganisms responsible for many common human diseases will be introduced in terms of their clinical, therapeutic, and epidemiological aspects as well as their molecular mechanisms of pathogenesis using an organ system approach. Topics will include immunology, bacteriology, virology, mycology, parasitology and microbial pathogenesis. Fall. Three 50-minute periods. Felise
BIOL310. Vertebrate Anatomy. An in-depth exploration of the structure and function of vertebrate animals in an evolutionary context. Laboratory exercises examine the structural diversity of vertebrate organ systems through dissection of representative vertebrate classes. This course is designed to provide a strong foundation in anatomy for students going on to a graduate or professional school in the human health or veterinary sciences. Prerequisite: Biology 112. Fall. Three 50-minute periods, one 3-hour laboratory. Irish
BIOL327. Biochemistry I. (also Chemistry 327). Structural features of the four major classes of biomolecules and basic functions of these molecules in cells. Fundamentals of information flow in biological systems, enzyme kinetics and catalytic mechanisms will set the stage for BIOL/CHEM 328 (Biochemistry II). Introduction to many of the techniques used in biochemistry laboratories and how to investigate biochemical problems. Prerequisites: Biology 265 and Chemistry 211. Fall. Three 70-minute periods, one 3-hour laboratory. Sh. Dunham
BIOL328. Biochemistry II. (also Chemistry 328). Designed to expand a student's background in biochemistry beyond a review of the introduction to biomolecular structure and function provided in Biochemistry I. A variety of advanced topics will be discussed including: metabolic pathways and strategies for the integration of pathways and the regulation of metabolism; membrane transport mechanisms; mechanisms of catalysis and design of active sites of enzymes/enzyme kinetics; signal transduction and the hormonal control of cellular metabolism and gene expression; and aberrations in gene expression/cellular signaling in human disease. Prerequisites: Biology 327 and Chemistry 212. Two 70-minute periods, one 3-hour laboratory. Husic
BIOL350. Human Physiology. Functions of vertebrate organ systems, with emphasis on the human body. Topics include the circulatory, digestive, nervous, muscular, hormonal, sensory, and excretory systems. Laboratory work emphasizes experimental techniques to analyze functional activities of animals. Prerequisites: Biology 112 and Chemistry 113–114. Three 50-minute periods, one 3-hour laboratory. Fox
BIOL351. Plant Physiology. Important physiological functions in higher plants and relationships between these functions and the structural organization of plants. Topics include water relations and water balance, mineral nutrition, transport phenomena, assimilate allocation and partitioning, plant metabolism, stress physiology, defense strategies against herbivores and pathogens, plant growth and development (germination, flowering, dormancy, plant hormones and growth regulators). Laboratory includes a core of experiments designed to illustrate important concepts in plant physiology and a research project of the student's choice, investigative and open-ended in character. Prerequisites: Biology 119 and Chemistry 113. Three 50-minute periods, one 3-hour laboratory. Bevington
BIOL360. Ecology. Interactions between organisms and their environment that determine their distribution and abundance in nature. Attention to evolutionary adaptation of species, population dynamics, community structure and function, and ecosystem analysis. Laboratory emphasizes qualitative and quantitative field investigations. Prerequisites: Biology 112 and 119 or permission of instructor. Fall. Alternate years. Three 50-minute periods, one 3-hour laboratory. Kuserk
BIOL362. Neuroscience. Study of neuroanatomy, neurophysiology and neuropathology; special emphasis on functional aspect of brain organization; introduction to theories and research regarding neurodegenerative disorders through journal club discussions. Laboratory includes gross anatomy and microscopic study of the central nervous system, computer-assisted neurophysiology experimentation, computerized and radiographic study of the brain and a semester-long behavior project. Prerequisites: Biology 112. Three 50-minute periods, one 3-hour laboratory. Fox
BIOL363. Genomics. An exploration of the techniques used to create genomic DNA libraries, to sequence the resulting DNA fragments, and to analyze the sequences of these fragments, at both the gene and genome levels. Students will gain familiarity with the computer programs used to assemble and annotate genomic sequence data as they use them to analyze their own raw data from the Washington University Genome Sequencing Center. This course will be extensively computer-based. We will be working with large (ca. 40-kb) sections of genomic DNA in silico: by the end of the semester, each student will have finished improving the sequence quality of one or two of these 40-kb clones to a publishable level and extensively annotated them, indicating the locations of genes, repeat sequences, and other sequence motifs. Prerequisite: Biology 210 and permission of the instructor. Alternate years. Two 70-minute periods. Jones
BIOL365. Molecular Genetics. Advanced genetics course emphasizing current knowledge and research in fundamental molecular aspects of genetics, primarily in eukaryotes. Topics include genome struture, transcriptional control, genetic regulatory pathways, and recombinant DNA technology. Prerequisites: Biology 210 and junior or senior standing. Alternate years. Three 50-minute periods, one 3-hour laboratory. Jones
BIOL370. Biology Seminar. Writing-intensive seminar in an area of biological science. Students will research and present written and oral reports on the general topic. Emphasis on the development of skills in using biological literature, analysis and interpretation of data, and communication of ideas. Prerequisite: Senior status or permission of instructor. Fall. Three 50-minute or two 70-minute periods. Staff. Writing-intensive.
BIOL375.2. Senior Seminar in Biochemistry. (also Chemistry 375.2).Advanced topics in biochemistry, designed to provide senior-level students with an opportunity to explore projects that illustrate how concepts from biology and chemistry relate to the study of biochemistry. Emphasis on development of ability for independent analysis of biochemical problems. Includes lectures by visiting speakers on current research. Students also will complete literature research, submit written reports, and make oral presentations on a biochemical topic chosen in consultation with faculty advisor. Prerequisite: Biology/Chemistry 328 or permission of instructor. One 120-minute period. St. Dunham. Writing-intensive.
BIOL390. Special Topic: Animal Development. The process by which multicellular organisms increase in complexity as they grow from single cell to adult. By considering classical embryology and recent advances in cellular and molecular biology, we will take up the most interesting questions of developmental biology, including how individual cells "know" where they are in the developing animal, similarities and differences in developmental processes, how an organism self-corrects developmental mistakes, and the role of development in evolution. Topics include fertilization, regulatory genetic cascades, cell-fate determination, emergence of complex organ systems, and handedness in organisms from slime molds to vertebrates. Prerequisites: Biology 112 and 210. Alternate years. Two 70-minute periods, one 3-hour laboratory. Irish & Jones
BIOL390.2. Special Topic: Directed Research in Biology. This half-credit course will enable selected students to conduct research under the direct supervision of the sponsoring faculty member. Project specifics and scheduling will be determined jointly by the faculty member and the student. It is expected that this course will require the equivalent of approximately 40 hours of student time over the semester. Jones
BIOL393. Special Topic: Major Transitions in Vertebrate Evolution. This course will focus on the structural and functional changes underlying major transitions in vertebrate evolution. Following introductory lectures, students will read papers from the primary literature exploring current controversies on such topics as the origin of vertebrates, the emergence of tetrapods onto land, the extinction of the dinosaurs, the evolution of endothermy, and the rise of birds and mammals. Students will be expected to come to class with written critiques for each article and questions and ideas to present for discussion. Students will also be required to present and lead the discussion for one or more articles from the primary literature, and research a topic of their choice for presentation at the end of the semester. Prerequisite: Biology 112 and at least one additional Biology course. Two 70-minute periods. Irish
BIOL394. Special Topic: Evolution. For more than a century evolution has been the unifying theory of biology. The late Theodosius Dobzhansky once remarked, "Nothing in biology makes sense…except in the light of evolution." From Charles Darwin's publication On the Origin of Species by Means of Natural Selection in 1859, through the development of the Modern Evolutionary Synthesis during the first half of the 20th century, to current theories on the mode and tempo of evolutionary change, evolutionary biology has played a key role in our understanding of how the natural world functions and changes over time. This course will explore evolutionary biology from several aspects, including the development of evolution as a theory, the importance of population genetics and natural selection as elements of evolutionary change, and the roles of reproductive isolation and hybridization on the origin of species. An emphasis will be placed on current evolutionary concepts and ideas such as the theory of punctuated equilibrium, the neutral theory of molecular evolution, and mosaic evolution. Discussions of major evolutionary trends, including the origins of humankind, will complete the course. Laboratory exercises, computer simulations and field trips to museums will focus on examining evidence for evolutionary principles. Prerequisite: Biology 210. Two 70-minute periods, one 3-hour laboratory. Kuserk
BIOL190-199, 290-299, 390-399. Special Topics.
BIOL286, 381-384. Independent Study.
BIOL288, 386-388. Internship.