abstracts

Joiner, M., Z. Asztalos, C.J. Jones, T. Tully, C.-F. Wu. 2000. "Effects of Mutant Drosophila K+ Channel Subunits on Habituation of the Olfactory Jump Response." Journal of Neurogenetics 21(1):45-58.

The olfactory-jump response assay was used to analyze habituation in Drosophila mutants of potassium (K+) channel subunits. As with physiological assays of the giant fiber-mediated escape reflex, mutations at loci that encode K+ channel subunits have distinct effects on habituating the olfactory-jump response. The data for slowpoke and ether à go-go indicate similar effects on habituation of the olfactory-jump response and the giant fiber-mediated escape. Habituation in the olfactory jump assay in Hyperkinetic and Shaker mutants was drastically different from the degree of defect in the giant fiber-mediated escape reflex, indicating differential control mechanisms underlying the two forms of non-associative conditioning.